Menstrual factors and cancer risk among Korean women

초록

Methods A total of 443 909 women, in the age group of 30-80 years in the 1993-94 time period were included in the analysis. During 12 years of follow-up, 17 959 incident cancer cases were identified by record linkage to the Central Cancer Registry database. Results Early age at menarche was associated with an increased risk of breast cancer and a decreased risk of stomach and gallbladder cancer. Later age at menopause was associated with an increased risk of breast cancer. When the analysis was restricted to post-menopausal women, the associations of age at menarche and menopause with cancers of the breast, stomach and gallbladder persisted. Conclusion These findings suggest that female hormonal factors play a significant role in the development of cancer in Korean women.

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