Elevated CEA is associated with worse survival in recurrent rectal cancer

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20
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23

초록

This study investigated the prognostic impact of serum carcinoembryonic antigen (CEA) level in recurrent rectal cancer. We reviewed 745 patients who developed recurrence after curative treatment for rectal cancer between January 2000 and December 2012. Multivariate analyses for survival revealed that age > 60 years (p =0.005), r-CEA >= 5 ng/ml (p < 0.001), disease free interval (DFI) < 12 months (p < 0.001), and palliative or conservative treatment (p < 0.001) were unfavorable factors.

키워드

CEA; rectal cancer; recurrence; survival; COLORECTAL-CANCER; CARCINOEMBRYONIC ANTIGEN; PREOPERATIVE CHEMORADIOTHERAPY; NEOADJUVANT CHEMORADIOTHERAPY; CLINICAL-SIGNIFICANCE; TUMOR-MARKERS; FOLLOW-UP; SURGERY
제목
Elevated CEA is associated with worse survival in recurrent rectal cancer
저자
Cho, Won Kyung; Choi, Doo Ho; Park, Hee Chul; Park, Won; Yu, Jeong Il; Park, Young Suk; Park, Joon Oh; Lim, Ho Yeong; Kang, Won Ki; Kim, Hee Cheol; Cho, Yong Beom; Yun, Seong Hyeon; Lee, Woo Yong
DOI
10.18632/oncotarget.22511
발행일
2017-12-01
유형
Article
저널명
Oncotarget
권
8
호
62
페이지
105936 ~ 105941