Update on rare epithelial ovarian cancers: based on the Rare Ovarian Tumors Young Investigator Conference

  • Jang, Ji Yon Agnes; 
  • Yanaihara, Nozomu; 
  • Pujade-Lauraine, Eric; 
  • Mikami, Yoshiki; 
  • Oda, Katsutoshi; 
  • 외 14명
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20

초록

There has been significant progress in the understanding of the pathology and molecular biology of rare ovarian cancers, which has helped both diagnosis and treatment. This paper provides an update on recent advances in the knowledge and treatment of rare ovarian cancers and identifies gaps that need to be addressed by further clinical research. The topics covered include: low-grade serous, mucinous, and clear cell carcinomas of the ovary. Given the molecular heterogeneity and the histopathological rarity of these ovarian cancers, the importance of designing adequately powered trials or finding statistically innovative ways to approach the treatment of these rare tumors has been emphasized. This paper is based on the Rare Ovarian Tumors Conference for Young Investigators which was presented in Tokyo 2015 prior to the 5th Ovarian Cancer Consensus Conference of the Gynecologic Cancer InterGroup (GCIG).

키워드

Rare Diseases; Ovarian Neoplasms; CLEAR-CELL CARCINOMA; GRADE SEROUS CARCINOMA; PHASE-III TRIAL; METASTATIC MUCINOUS ADENOCARCINOMAS; PI3K/AKT/MTOR SIGNALING PATHWAY; FERTILITY-SPARING SURGERY; LYMPH-NODE METASTASIS; THERAPEUTIC TARGET; BORDERLINE TUMORS; INTESTINAL-TYPE
제목
Update on rare epithelial ovarian cancers: based on the Rare Ovarian Tumors Young Investigator Conference
저자
Jang, Ji Yon Agnes; Yanaihara, Nozomu; Pujade-Lauraine, Eric; Mikami, Yoshiki; Oda, Katsutoshi; Bookman, Michael; Ledermann, Jonathan; Shimada, Muneaki; Kiyokawa, Takako; Kim, Byoung-Gie; Matsumura, Noriomi; Kaku, Tsunehisa; Kuroda, Takafumi; Nagayoshi, Yoko; Kawabata, Ayako; Iida, Yasushi; Kim, Jae-Weon; Quinn, Michael; Okamoto, Aikou
DOI
10.3802/jgo.2017.28.e54
발행일
2017-07
유형
Review
저널명
Journal of Gynecologic Oncology
권
28
호
4