Impulsivity between the Acute Manic Episode and the Improved State of Manic Episode in Bipolar Patients

초록

Objectives : The higher prevalence of suicidality and substance abuse among bipolar patients could be explained by their relation with impulsivity. This current study investigates the impulsivity change in bipolar patients when the clinical course changes from the acute manic phase to the improved state of manic episode. Methods : The Seventeen acute manic bipolar patients, enrolled were evaluated with Young Mania Rating Scale and Hamilton Depression Rating Scale. Self-reported scales [Mood Disorder Questionnaire, Hypomania/mania symptom Checklist-32, Beck Depression Index, Barratt Impulsiveness Scale-11-revised (BIS-11-R), Temperament and Character Inventory-Revised Short Version (TCI-RS)] were obtained and the behavioral impulsivity was accessed by neuropsychology test (Conner’s Continuous Performance Task, Stroop Test). In subjects who achieved the improved state of manic episode, the self-report and neuropsychology test were retested. Results : Compared with manic state during the improved state of manic episode, the inattention subscale of BIS-11-R (p=0.002), commission error (p= 0.027), color (p=0.024), word (p=0.022), color-word (p=0.007), error score (p=0.034), NS scale of TCI-RS (p=0.003) were significantly decreased. However, there were no significant difference in other scales. Conclusion : Inattention impulsivity improved following the course of bipolar disorder but motor and unplanned Impulsivity persisted across the course, this can be applied for diagnosis and method of treatment.

키워드